Objective: This study examined whether spousal support, work-family conflict, and career satisfaction predict quality of life among working mothers in healthcare settings across Ibadan, Nigeria. Methods: The research adopted a cross-sectional survey design and utilised a purposive and convenience sampling procedure to select 391 working mothers from five major hospitals within Ibadan, Nigeria.

Data were collected using Spousal Support Scale, Work-Family Conflict Scale, Career Satisfaction Scale, and WHOQOL-BREF. Descriptive statistics summarised socio-demographic variables, while Pearson correlation and multiple regression analyses tested the hypotheses using SPSS v27. Results: Spousal support significantly and positively predicted quality of life (p