Objectives: To evaluate the demographic characteristics, lesion distribution, treatment approaches, complications, and clinicaloutcomes of pediatric patients with infantile hemangiomas (IHs) at a single tertiary center.Patients and Methods: We retrospectively reviewed 182 pediatric patients with IHs managed at Marmara University Pendik Trainingand Research Hospital between 2011 and 2023.
Demographic features, lesion characteristics, treatment approaches, complications,and outcomes were analyzed.Results: The cohort comprised 182 children, of whom 59.9% were female. The median age at presentation was 7 months (range: 1–198months). Prematurity and low birth weight were documented in 13.2% and 12.1% of patients, respectively.
Most patients (72.7%) hada single lesion; the liver (14.2%) and scalp (12.0%) were the most frequent sites. Ulceration occurred in 5.5% of cases. Active treatmentwas required in 60.7% of patients, with propranolol being the most commonly used therapy (37.7% of the cohort). Treatment-relatedadverse events were limited to one episode of hypoglycemia; no cardiac toxicity was observed.
Spontaneous regression predominatedin small, superficial, and asymptomatic lesions.Conclusion: Infantile hemangiomas generally follow a benign clinical course, and observation is appropriate for low-risk lesions.High-risk or complicated lesions warrant active management, with propranolol remaining the standard systemic therapy.
Multicenterprospective studies are needed to refine risk stratification and optimize individualized treatment.