Assessment of the correlation between MRI texture analysis findings and histopathological diagnoses in solid liver lesions

Objective: To evaluate the diagnostic value of texture analysis in differentiating benign and malignant liver lesions, as well asdistinguishing primary malignant liver tumors from metastases using pre-contrast magnetic resonance imaging (MRI) sequences.Materials and Methods: This retrospective study included 101 liver lesions from 100 patients who underwent upper abdominal MRIfollowed by biopsy or surgical resection.

Texture analysis was performed on pre-contrast T1-weighted (T1W), T2-weighted (T2W),and apparent diffusion coefficient (ADC) sequences using first-order (histogram-based) and second-order (gray level co-occurrencematrix (GLCM)-based) statistical parameters. Group comparisons were conducted using Mann-Whitney U test, with a significancethreshold of p